Molecular Detection of Oral Helicobacter pylori and Its Association with Dental Conditions Among Patients with Helicobacter Infection in Baghdad City

Dhari Alewi, Marwa; Taha Mohammed, Ahlam

doi:10.30699/ijmm.17.4.406

year 17, Issue 4 (July - August 2023) Iran J Med Microbiol 2023, 17(4): 406-413 | Back to browse issues page

‎ 10.30699/ijmm.17.4.406

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Dhari Alewi M, Taha Mohammed A. Molecular Detection of Oral Helicobacter pylori and Its Association with Dental Conditions Among Patients with Helicobacter Infection in Baghdad City. Iran J Med Microbiol 2023; 17 (4) :406-413
URL: http://ijmm.ir/article-1-2187-en.html

Molecular Detection of Oral Helicobacter pylori and Its Association with Dental Conditions Among Patients with Helicobacter Infection in Baghdad City

Marwa Dhari Alewi

¹, Ahlam Taha Mohammed²

1- Department of Preventive Dentistry, College of Dentistry, University of Baghdad, Baghdad, Iraq , marwadhari1989@gmail.com
2- Department of Preventive Dentistry, College of Dentistry, University of Baghdad, Baghdad, Iraq

Abstract: (808 Views)

Background and Aim: Helicobacter pylori is found in the stomach and the oral cavity, which plays a significant role in oral diseases and recurrent gastric infections. This study aimed to detect the presence of oral H. pylori and investigate its potential association with dental caries and erosion.
Materials and Methods: Saliva and plaque samples were collected from two groups: a study group of 40 H. pylori-infected patients, confirmed by immunological tests, and a control group included 40 subjects who were given negative results after laboratory examination. Molecular detection of H. pylori was performed using the polymerase chain reaction (PCR). Additionally, clinical assessments of dental caries and erosions were conducted.
Results: The study group showed a higher prevalence of H. pylori in saliva (62.5%) compared to dental plaque (45.0%). Among the study group, 70% tested positive for H. pylori by PCR, while 30% tested negative. Dental caries experience (DMFS) was slightly higher in the study group compared to the control group, and significant differences in (DS) and (DMFT) (p<0.05). The prevalence of dental erosion was also higher in the study group compared to the control group.
Conclusion: The presence of H. pylori in the oral cavity represents an important risk factor for dental caries and erosion.

Keywords: Helicobacter pylori, PCR, Dental erosion, Saliva

Full-Text [PDF 526 kb] (583 Downloads) | | Full-Text (HTML) (154 Views)

Type of Study: Original Research Article | Subject: Oral Microbiology
Received: 2023/05/18 | Accepted: 2023/08/25 | ePublished: 2023/09/27

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